Elastin Products Company 产品列表和技术资料（三）

百度网盘下载

EPC Elastin Products Company 是一家有着30多年悠久历史的高科技生物制品公司，为大量生物制药企业、研究院所提供各类科研级生化试剂，用于动物实验及体外测试类研究。Elastin 所有产品均供研究动物实验室使用和体外测试，禁止任何产品用作食品或药物或人类。

Elastin 产品包括琼脂糖衍生产品、抗弹性蛋白抗体、抗微纤丝蛋白抗体、抗蛋白酶抗体、生物活性肽、胶原蛋白、胶原酶及其抑制剂、金属基质蛋白酶、偶联氨基酸/抗血清、弹性蛋白酶底物、弹性蛋白肽、（人）弹性蛋白、人胰蛋白酶、人唾液白细胞酶、大/小鼠、牛胰蛋白酶、各种底物、羧肽酶等。

Elastin Products Company 产品列表

bioactive peptides/collagenase/cross linking amino acids/cross-linking-antisera/cold packing/carboxpeptidase/collagenase inhibitor

货号	名称	规格	产品描述
BP259	BP259, Leu-Gly-Thr-Ile-Pro-Gly, 1 mg	1mg	Purity: 95-98% pure by HPLC Repeating peptide in laminin, chemotactic for inflammatory cells, fibroblasts, smooth muscle cells and tumor cells. Prepared by synthesis (49). The peptide is soluble in all aqueous buffers.
BP534	BP534, Val-Gly-Val-Ala-Pro-Gly, 1 mg	1mg	Purity: 95-98% pure by HPLC Repeating peptide in elastin, chemotactic for inflammatory cells, fibroblasts, smooth muscle cells and tumor cells. Prepared by synthesis (48). The peptide is soluble in all aqueous buffers.
IP304	IP304, Collagenase Inhibitor		Isoamylphosphonyl-Glycyl-Prolyl-L-Alamine, dipotassium salt. F.W. 454 Prepared by the methodof Galardy and Grobelny(26). Puritey is determined by thin layer chromatography and NMR. The purity is 95%. A 1 µM concentration completely inhibits 20 µM concentration completely inhibits 20µM of collagenase from Clostridium histolyticum (Ki = 20 µM). The inhibitor can be coupled to aminohexyl-agarose by reaction with EDC to yield an affinity gel (28) suitable for purification of collagenase (27).
CP404	CP404, Collagenase Inhibitor, 5mg	5mg	5-(R,S)-t-trans-cinnamido-7-methyl-4-oxo-octanoyl-L-Protyl-L-Proline. F.W. 512 Prepared by the method of Grobelny and Galardy (26). Purity is 95% as determined by thin layer chromatography and NMR. Inhibits Clostridium histolyticum collagenases.
AP405	AP405, Collagenase Inhibitor, 5mg	5mg	O-ethy-N-phospho-Isoleucyl-(O-benzyl-L-Tyrosyl)-Glycine dipotassium salt. F.W. 625 Prepared by the method of Galardy and Grobelny (26). Purity is 95% as determined by thin layer chromatography and NMR. Inhibits human skin fibroblast collagenase.
CC203	CC203, Collagenase	100mg 500mg 1g 5g	EC 3.4.24.3 SOURCE. Cl. Histolyticum. SPECIFICATIONS.Crude. Approximately 95% soluble, contains ca. 2% salts, Tris pH 7.5 and CaCl2. Store 5° C. Will remain stable 12-24 months at 5°C. Clostripain Activity; <0.5 units per mg of protein. One unit will hydrolyze 1 µmole of N-benzoyl-DL-arginine-pNA (BAPNA) per minute at pH 8.0 and 25° C with 3 mM dithiothreitol.
CL103	CL103, Collagenase High-Purity	10000units 25000units 50000units 200000units	SOURCE. CI Histolyticum. SPECIFICATIONS. Chromatographically purified, salt-free, lyophilized water soluble powder. Store at 5° C. Will remain stable 9 to 12 months at 5° C. 1000-2000 units per mg of protein. One unit will liberate a ninhydrin color equivalent to 1 µM of L-leucine at pH 7.5 in 5 hours at 37°C. Bovine achilles tendon collagen (EPC No. C204) is the substrate. Also, 8-12 FALGPA units per mg of protein where 1 unit will hydrolyze 1 µmole of furanacryloyl-Leu-Gly-Pro-Ala at pH 7.5 per minute. (53).
CP303	CP303, Collagenase	5000units 10000units 25000units 50000units 200000units	SOURCE. Cl. Histolyticum. SPECIFICATIONS.Partially purified by chromatography of crude collagenase (EPC No. CC203). Store 5°C. Will remain stable for 9-12 months at 5° C. COLLAGENASE ACTIVITY; 350-450 units per mg of protein. One unit will liberate a ninhidrin color equivalent to 1 µmole of L-leucine in 5 hours at 37° C. The buffer-substrate medium is 5 ml of 0.1 M Tris-HCI pH 7.5 containing 0.01 M CaCl2 and 25 mg collagen (EPC No. C204).
DOC375	DOC375, Desmosine-Ovalbumen Conjugate, 1 vial	1 vial	To use for coating microtiter plates for desmosine ELISA. Prepared by the method of Starcher (8) by coupling ovalbumen (egg albumen) with the coupling reagent EDC. Product is very soluble in water or buffers. Replaces product no. DA855, desmosine conjugated to albumen due to solubility problems. Each vial contains enough coating material to coat twenty 98 well plates. Recommended to dissolve in 1 ml water and dilute as necessary in coating buffer for the number of places required, store the remainder at 5°C.
MD687	MD687, Desmosine and Isodesmosine (Equimolar Mixture), 1 vial contains 5 mg	5mg
DR44	DR44, Desmosine and Isodesmosine Standard (Equimolar Mixture), 1 vial	1 vial
D866	D866, DESMOSINE		Desmosine is prepared according to the method of Starcher et al. (7) from hydrolyzed bovine neck ligament by solvent extraction and chromatography on Dowex 50. Purity is determined by amino acid analysis and by thin layer chromatography. Rt = 0 butanol / acetic acid / water (4:1:1). The purity is 90-95% plus/minus 0.2%. Anydrous MW is 526. Desmosine is extremely hygroscopic and must be stored over a desiccant such as silica gel. The following package quantities are prepared within plus/minus 0.1 mg under desiccated conditions. Desmosine and isodesmosine are very stable amino acids. They survive autoclaving and boiling in sodium hydroxide during purification. The only thing that happens during time, provided they are not kept away from moisture, is they may darken a little and become a gel. They are extremely hydroscopic
DA878	DA878, DESMOSINE ANTISERUM, 1 ml	1ml	Antigen: Isodesmosine covalently linked to keyhole limpets hemocyanin. Host: Rabbit Supplied as lyophilized 1 ml aliquots of whole antiserum. No species specificity.Reconstitute to 1 ml with water 5° C. For RIA, dilute the reconstituted antiserum to 1/40 and use 25-50 µl per test.
CT455	CT455, ISODESMOSINE ANTISERUM, 1 ml	1ml	Antigen: Isodesmosine covalently linked to keyhole limpets hemocyanin. Host: Rabbit Supplied as lyophilized 1 ml aliquots of whole antiserum. No species specificity.Reconstitute to 1 ml with water 5° C. For RIA, dilute the reconstituted antiserum to 1/40 and use 25-50 µl per test.
CBW196	CBW196, Carboxypeptidase W, wheat germ		SOURCE. Wheat germ. SPECIFICATIONS. Chromatographically purified and 1 x crystallized, suspension in 2.5 M NaCl + NaOAc, pH 4.0. Protein concentration 2 - 10 mg/ml 120 - 140 units per mg of protein 1 unit will hydrolyze 1.0 mmole of N-CBZ-Phe-Ala per minute at pH 4 and 30°C, assay per Umetsu, et.al., Food Chem, Vol 7, p.125 (1981).
CB104	CB104, Human Pancreatic Carboxypeptidase B, 0.1 mg	0.1mg
CA906	CA906, Human Pancreatic Carboxypeptidase A, 0.1 mg	0.1mg	SPECIFICATIONS. Chromatographically purified from human pancreas. Frozen solution in 0.05M NaOAc pH 5.0 + 1.0 M NaCl. MW-35,000 50 - 55 units per mg of protein. Store frozen at approximately -20°C. Concentration (A280 x 1.45)-(A260 x 0.74) = mg/ml.
IP304	IP304 Collagenase Inhibitor		SPECIFICATIONS. Chromatographically purified from human pancreas. Frozen solution in 0.05M NaOAc pH 5.0 + 1.0 M NaCl. MW-35,000 50 - 55 units per mg of protein. Store frozen at approximately -20°C. Concentration (A280 x 1.45)-(A260 x 0.74) = mg/ml.
GM6001	GM6001, Matrix Metalloprotease Inhibitor, 5 mg	5mg
AP405	AP405, Collagenase Inhibitor, 5mg	5mg	O-ethy-N-phospho-Isoleucyl-(O-benzyl-L-Tyrosyl)-Glycine dipotassium salt. F.W. 625 Prepared by the method of Galardy and Grobelny (26). Purity is 95% as determined by thin layer chromatography and NMR. Inhibits human skin fibroblast collagenase.
CP404	CP404, Collagenase Inhibitor, 5mg	5mg	5-(R,S)-t-trans-cinnamido-7-methyl-4-oxo-octanoyl-L-Protyl-L-Proline. F.W. 512 Prepared by the method of Grobelny and Galardy (26). Purity is 95% as determined by thin layer chromatography and NMR. Inhibits Clostridium histolyticum collagenases. Ki = 1 µM for B-collagenase, 18 nM for E-collagenase, complete inhibition at 20 µM. The inhibitor is hygroscopic and should be stored over desiccant.