methyldetect品牌介绍

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methyldetect

品牌简介

DNA甲基化是研究最广泛的基因表达调控表观遗传学机制之一。越来越多的基因异常甲基化被证明会导致大多数疾病，如癌症、心血管疾病、衰老、肥胖、过敏、糖尿病、抑郁症、阿尔茨海默氏症、帕金森氏症或精神分裂症。
可靠的研究证据已经表明，基于DNA甲基化的生物标记物可用于临床疾病管理的所有阶段，包括：
疾病风险评估
早期发现
个性化治疗
慢性疾病和复发的监测
这项技术已经在法医学等领域用于检测DNA甲基化生物标记物，并用于研究具有挑战性的DNA材料来源，如液体活检和FFPE组织。
MethylDetect提供用于检测异常基因甲基化的现成试剂盒。该试剂盒基于MS-HRM（甲基化敏感高分辨率熔融）技术，可与标准实验室设备一起使用。此外，每个套件附带的新控制系统提供了最先进的实验可靠性。

DNA Methylation is one of the most widely studied epigenetic mechanisms of gene expression regulation. Aberrant methylation of increasing number of genes is being shown to contribute to the majority of diseases such as cancer, cardiovascular disorders, aging, obesity, allergy, diabetes, depression, Alzheimer’s, Parkinson’s or schizophrenia.

Solid research evidence already shows that DNA methylation-based biomarkers can be utilized at all stages of clinical disease management including:

Disease risk assessment

Early detection

Personalization of treatment

Monitoring of chronic disorders and recurrence

The technology is already in use for detection of DNA methylation biomarkers in fields like forensics, and for investigating challenging DNA materiel sources as liquid biopsies and FFPE tissues.

MethylDetect offers ready-to-use kits for detection of aberrant gene methylation. The kits are based on the MS-HRM (Methylation Sensitive High Resolution Melting) technology and can be used with standard laboratory equipment. Additionally, our new controls system shipped with each kit, provides state-of-the-art experimental reliability.

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